Symptoms
Security must be initialised before any interfaces are marshalled or unmarshalled. It cannot be changed once initialized. (CoInitialzeSecurity).
Cause
Backup of Exchange using 32bit DS-Client (Windows 2008 SP2, Windows 7, Windows 8 or Windows 10). This happened after applying hotfix#5 (13.3)
Workaround
Suggest to use 64bit DS-Client.
Starting with v.13.3.0.5, only Windows DS-Client 64bit supports Exchange backups"